mp3®

The injectable Dual-Phase xenograft

The product

mp3® is a Dual-Phase pre-hydrated biomaterial. It is possible to skip the hydration phase and decrease the risk of accidental exposure of the material to pathogens during the manipulation phase.

Dual-Phase granules are endowed with characteristics very similar to autogenous bone¹, and can be used as a viable alternative to AB providing similar performances over time². mp3® granules are gradually resorbable³⁻⁴, and preserve the original shape and volume⁵.

mp3® is made of a collagenic bone mix pre-hydrated with collagen gel.

MP3_SEM_PRODOTTI

Source: Politecnico di Torino, Torino, Italy

Histology illustrating the healing after 6 months from mp3® grafting in human. Newly formed bone (#) can be detected around and in between Dual-Phase bone granules (*). 

ISTOLOGIA_mp3_UOMO_PER_PRODOTTI

Courtesy of Prof. Ulf Nannmark, Göteborg University, Sweden. 

mp3® is ready-to-use, pre-hydrated and can be easily grafted into an antrostomy or post-extractive sockets.

Dentist

Why choosing mp3®?

Although autogenous bone (AB) is still the gold standard for bone regeneration, it takes time to harvest it. Biomaterials are used as alternatives to AB, with the advantage of unlimited availability and reduced invasiveness. mp3® is a ready-to-use Dual-Phase biomaterial that can be directly syringed into sinus cavities, showing comparable results to autogenous bone chips¹⁻². Thanks to its similarity to natural human bone¹, mp3® has been easily syringed and successfully used in combination with Evolution membranes for alveolar ridge preservation, maintaining appropriate alveolar ridge volume and allowing a correct second-stage implant placement⁵. These unique properties allow a good graft volume preservation⁵, a healthy new bony tissue formation and ultimately, a successful implant rehabilitation over time⁶⁻⁸.

 

mp3 7RB00015

How to handle mp3®

mp3® must be used in a sterile environment. After adapting the material to the defect shape, it is necessary to remove non-stable residues before proceeding to the soft tissue suture.

References
  1. Correia F et al. Materials (Basel), 2021 Jun 21;14(12):3439
  2. Correia F et al. Dent J (Basel), 2024 Feb 3;12(2):33
  3. Nannmark U et al. Clin Implant Dent Relat Res, 2008 Dec;10(4):264-70
  4. Giuliani A et al. Clin Oral Investig, 2018 Jan;22(1):505-513
  5. Barone A et al. Clin Oral Implants Res, 2016 Nov;27(11):e105-e115
  6. Pistilli R et al. J Dent, 2022 Jun;121:104137
  7. Buonocunto N  et al. Clin Implant Dent Relat Res, 2023 Dec;25(6):1044-1055
  8. Cinquini C et al. Clin Implant Dent Relat Res, 2024 Dec;26(6):1162-1171
Image
mp3 - Packaging
Technical specifications

Description

  • Collagenic bone mix granules pre-hydrated with collagen gel
  • Pre-hydrated granules and collagen gel
  • Heterologous bone mix
Porcine origin
Codes Size Type Granulometry Re-entry time
A3095FS 0.5 cc 1 Syringe 600-1000 μm About 5 months
A3005FS 1 cc 1 Syringe 600-1000 μm About 5 months
A3010FS 2 cc 1 Wide-tip syringe 600-1000 μm About 5 months
A3210FS 2 cc 1 Wide-tip syringe 1000-2000 μm About 5 months
Equine origin
Codes Size Type Granulometry Re-entry time
A3095FE 0.5 cc 1 Syringe 600-1000 μm About 5 months
A3005FE 1 cc 1 Syringe 600-1000 μm About 5 months
A3010FE 2 cc 1 Wide-tip syringe 600-1000 μm About 5 months
A3210FE 2 cc 1 Wide-tip syringe 1000-2000 μm About 5 months

Clinical cases

Horizontalregenerationandimplantplacement _cover

Horizontal regeneration and implant placement after dental trauma in the aesthetic area

Dr. Michele Antonio Lopez

mp3® | Evolution | Lamina®

Horizontal augmentation

SinusGraftcombinedwith3D_cover

Sinus graft combined with 3D alveolar reconstruction

Dr. Ferdinando D Avenia

mp3® | Derma | Evolution

Lateral access sinus lift

GBRwithSoftBoneLamina_cover.jpg

GBR at the same time of implant placement

Prof. Michael Weinländer

mp3® | Lamina®

Horizontal augmentation

Evolution and mp3 are used to treat a periodontal defect

The Modified Papilla Preservation Technique

Dr. Gerd Körner

mp3® | Evolution

Periodontal regeneration

Next Courses

Testori LCI OsteoBiol course 2025 - Front page

Course on Sinus augmentation

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Como, Italy

Prof. Tiziano Testori, Prof. Marco Esposito & Dr. Matteo Invernizzi

Selected bibliography

Open Access

Advantages of porcine xenograft over autograft in sinus lift: a Randomised Clinical Trial

Materials, 2021 Jun 21;14(12):3439

Correia F, Pozza DH, Gouveia S, Campos Felino A, Faria Almeida R
Open Access

Guided implant surgery and sinus lift in severely resorbed maxillae: a retrospective clinical study with up to 10 years of follow-up

J Dent, 2022 Jun;121:104137

Pistilli R, Canullo L, Pesce P, Pistilli V, Caponio C, Sbricoli L
Open Access

Alveolar ridge preservation and its impact on marginal bone level changes around dental implants: a retrospective, cohort comparative study

Clin Implant Dent Relat Res, 2024 Dec;26(6):1162-1171

Cinquini C, Izzetti R, Porreca A, Iezzi G, Nisi M, Barone A
Copyrighted

Extra oral digital scanning and imaging superimposition for volume analysis of bone remodeling after tooth extraction with and without 2 types of particulate porcine mineral insertion: a randomized controlled trial

Clin Implant Dent Relat Res, 2017 Aug;19(4):750-759

Barone A, Toti P, Menchini Fabris GB, Derchi G, Marconcini S, Covani U
Open Access

Collagenated porcine heterologous bone grafts: histomorphometric evaluation of bone formation using different physical forms in a rabbit cancellous bone model

Molecules, 2021 Mar 2;26(5):1339

Falacho RI, Palma PJ, Marques JA, Figueiredo MH, Caramelo F, Dias I, Viegas C, Guerra F
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