Apatos®

Microcrystalline hydroxyapatite

The product

Apatos® is a biocompatible and osteoconductive¹ collagenic xenograft with characteristics similar to mineralised human bone².

The natural microporous consistency of Apatos® facilitates the formation of new bone tissue in the bone defect area³, accelerating the physiological process. Apatos® Cortical is characterised by a long resorption time⁴, contributing to the preservation of the grafted volume.

Apatos® is a dry cortico-cancellous collagenic bone mix.

 

GEN_APATOS_SEM_PRODOTTI

Source: Politecnico di Torino, Torino, Italy

Apatos® can be mixed with the patient's blood and can be used to preserve the volume of bony lesions and treat two-wall defects and molar or premolar extraction sockets.

Dentist

Why choosing Apatos?

Because of its capacity to maintain the volume⁵⁻⁶ and its medium-sized granulometry, Apatos® is the proper ally for dentists' daily practice.

Hence, Apatos® has been used as a valid alternative to autologous bone to regenerate and preserve the volume of bony lesions, treat two-wall defects⁷ and molar or premolar extraction sockets³. When needed, Apatos® can be protected with Evolution membranes⁸ or stabilised with Lamina®.

handle-apatos

How to handle Apatos®

Apatos® must always be hydrated and thoroughly mixed with a few drops of sterile saline; it can also be mixed with the patient’s blood. The mixture thus obtained should be positioned with a sterile spatula or syringe for biomaterials.

References
  1. Cakir M et al. Int J Oral Maxillofac Implants, 2015 Mar-Apr;30(2):2
  2. Kolmas J et al. J Pharm Biomed Anal, 2012 Mar 5;61:136-41
  3. Barone A et al. Clin Oral Implants Res, 2016 Nov;27(11):e105-e115
  4. Scarano A et al. Clin Implant Dent Relat Res, 2011 Mar;13(1):13-8
  5. Menini M et al. Dent J (Basel), 2024 Jun 27;12(7):198
  6. Barone A et al. Clin Implant Dent Relat Res, 2017 Aug;19(4):750-759
  7. Barone A et al. Clin Implant Dent Relat Res, 2015 Dec;17(6):1114-26
  8. Marconcini S et al. Clin Implant Dent Relat Res, 2018 Dec;20(6):906-914
  9. Köttgen C et al. Int J Esthet Dent, 2024 May 10;19(2):152-169
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Apatos - Packaging
Technical specifications

Description: 

Radiopaque granules of mineral hydroxyapatite

Apatos® Mix: Dry cortico-cancellous collagenic bone mix
Apatos® Cortical: Dry cortical collagenic bone granules
 

Porcine origin
Codes Size Type Granulometry Re-entry time
A1005FS 0.5 g 1 Vial 600 - 1000 μm About 5 months
A1010FS 1 g 1 Vial 600 - 1000 μm About 5 months
A1020FS 2 g 1 Vial 600 - 1000 μm About 5 months
A0210FS 1 g 1 Vial 1000 - 2000 μm About 5 months
Equine origin
Codes Size Type Granulometry Re-entry time
A1005FE 0.5 g 1 Vial 600 - 1000 μm About 5 months
A1010FE 1 g 1 Vial 600 - 1000 μm About 5 months
A1020FE 2 g 1 Vial 600 - 1000 μm About 5 months
A0210FE 1 g 1 Vial 1000 - 2000 μm About 5 months

Clinical cases

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Vertical and horizontal reconstruction of the esthetic area

Dr. Iñaki Gamborena

Apatos® | Derma | Lamina®

Horizontal augmentation | Vertical augmentation

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Reconstruction of an atrophic mandible

Dr. Christopher Köttgen

Apatos® | Lamina®

Vertical augmentation

Complexfunctional_cover.jpg

Complex functional, periodontal, restorative and esthetical rehabilitation of a patient with severe periodontitis

Dr. Christopher Köttgen

Apatos® | Lamina®

Horizontal augmentation

Selected bibliography

Copyrighted

Extra oral digital scanning and imaging superimposition for volume analysis of bone remodeling after tooth extraction with and without 2 types of particulate porcine mineral insertion: a randomized controlled trial

Clin Implant Dent Relat Res, 2017 Aug;19(4):750-759

Barone A, Toti P, Menchini Fabris GB, Derchi G, Marconcini S, Covani U
Open Access

Effect of different graft material consistencies in the treatment of minimal bone dehiscence: a retrospective pilot study

Dent J (Basel), 2024 Jun 27;12(7):198

Menini M, Canullo L, Iacono R, Triestino A, Caponio VCA, Savadori P, Pesce P, Pedetta A, Guerra F
Copyrighted

Clinical outcomes of implants placed in ridge-preserved versus nonpreserved sites: a 4-year randomized clinical trial

Clin Implant Dent Relat Res, 2018 Dec;20(6):906-914

Marconcini S, Giammarinaro E, Derchi G, Alfonsi F, Covani U, Barone A
Copyrighted

Immediate implant placement in a dialysis patient. A case report

Int J Esthet Dent, 2024 May 10;19(2):152-169

Köttgen C, Köttgen I, Plaster U
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