Gel 40

A unique heterologous bone gel

The product

The composition of Gel 40 facilitates the gentle detachment of the sinus membrane¹.

Cortico-cancellous Dual-Phase granules provide the necessary scaffold function², allowing the subsequent invasion of regenerative cells and new bone formation¹⁻². Gel 40 provides an osteoconductive matrix for new bone growth, while promoting soft tissue healing, when used in narrow self-contained bone defects¹⁻².

 

 

Histology illustrating the healing after 6 months from Gel 40 grafting in human. Gel 40 small-diameter bone particles (*) appear surrounded and joined together by newly-formed bone (#). 

ISTOLOGIA_GEL40_UOMO_PER_PRODOTTI

Courtesy of Prof. Tonino Traini, Università degli Studi di Chieti-Pescara, Italy

Gel 40 is a collagenic bone gel pre-hydrated with collagen gel.

GEL40_SEM_PRODOTTI

Source: Politecnico di Torino, Torino, Italy

Gel 40 is ready-to-use, pre-hydrated and can be used for transcrestal sinus floor elevation protocols. 

Dentist

Why choosing Gel 40?

The perforation of the Schneiderian membrane is one of the major complications that may occur during transcrestal sinus floor elevation.
 

Various studies reported that Gel 40 simplifies the transcrestal sinus floor elevation¹’³⁻⁶ with immediate implant positioning: the collagen gel contained in Gel 40 gently detaches the sinus membrane making the surgery easier, faster¹, and predictable¹’⁶.
 

Finally, in case of accidental perforation of the Schneiderian membrane, Gel 40 bone granules accidentally dispersed into the sinus are easily extruded without major complications⁵.

handle-gel

How to handle Gel 40

The distinctive viscosity and density of Gel 40 facilitate the handling of the bone gel.

It was documented that, in case of adequate height of the bone crest, immediate implant placement reduces the physiological shrinkage of the biomaterial¹ in transcrestal sinus floor elevation.

References
  1. Lombardi T et al. Int J Implant Dent, 2022 Jul 22;8(1):32
  2. Kobe T et al. Clin Exp Dent Res, 2024 Feb;10(1):e853
  3. Barone A et al. Int J Periodontics Restorative Dent, 2008 Jun;28(3):283-9
  4. Santagata M et al. J Oral Implantol, 2010;36(6):485-489
  5. Bernardello F et al. Sinusitis, 2021, 5(2), 132–140
  6. Lopez MA et al. Am J Dent, 2024 Sept;37(SIA):25A-28A
Image
Gel 40 - Packaging
Image
gel40 7RB08091.jpg
Technical specifications

Description: 

  • Collagenic bone gel pre-hydrated with collagen gel
  • Pre-hydrated granules and collagen
  • Heterologous bone mix
Codes Size Type Granulometry Re-entry time
05GEL40S 0.5 1 Syringe Up to 300 μm About 4 months

Clinical cases

One-stagecrestal_cover

One-stage crestal sinus lift in a narrow sinus

Dr. Fabio Bernardello | Prof. Claudio Stacchi

Gel 40

Crestal access sinus lift

Gel 40 gently displaced the Schneiderian membrane

Transcrestal sinus floor elevation with the hydrodnamic technique

Dr. Fabio Bernardello

Gel 40

Crestal access sinus lift

TheEntirepapillae_cover.jpg

The Entire Papillae Preservation Technique (EPPT) for the treatment of a periodontal defect

Dr. Tom Kobe

Gel 40

Periodontal regeneration

Gel 40 is used to treat a periodontal defect

Treatment of periodontal with the NIPSA protocol

Dr. Tom Kobe

Gel 40

Periodontal regeneration

Videos

OsteoBiol - Gel 40 video
Crestal access sinus lift
OsteoBiol - Gel 40 (Crestal access sinus lift)

Selected bibliography

Open Access

Clinical and radiographic outcomes following transcrestal maxillary sinus floor elevation with injectable xenogenous bone substitute in gel form: a prospective multicenter study

Int J Implant Dent, 2022 Jul 22;8(1):32

Lombardi T, Lamazza L, Bernardello F, Zi?tek G, Stacchi C, Troiano G
Open Access

Transcrestal maxillary sinus floor elevation with injectable xenogeneic bone substitute in gel form: a clinical, radiological and histological analysis

Am J Dent, 2024 Sept;37(SIA):25A-28A

Lopez MA, Passarelli PC, Netti A, Felicetti A, Dell'Aquila F, Wychowański P, D'Addona A
Copyrighted

Healing of gingival recessions using a collagen membrane with a demineralized xenograft: a randomized controlled clinical trial

Int J Periodontics Restorative Dent, 2009 Feb; 29(1):59-67

Cardaropoli D, Cardaropoli G
Copyrighted

Short communication: collagenated cortico-cancellous porcine bone grafts. A study in rabbit maxillary defects

Clin Implant Dent Relat Res, 2010 Jun 1; 12(2):161-3

Nannmark U, Azarmehr I
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