Evolution

The natural Evolution of collagen membranes

The product

Evolution collagen membranes originate from xenogenic pericardium and peritoneum.

 

The membrane structure made of dense collagen fibres of high consistency and resistance makes it a valid choice to protect and stabilize the bone graft in most surgical procedures. These membranes are gradually resorbable¹ and showed great resistance to degradation in in vitro tests²⁻⁴.

Histology illustrating the healing after 2 weeks from Gen-Os® (*) and Evolution grafting in rabbits.

 

ISTOLOGIA_EVOLUTION_CONIGLI_PER_PRODOTTI

Courtesy of Prof. Daniele Botticelli, Scientific Director of ARDEC Academy, Italy

Evolution membranes originate from equine pericardium and porcine peritoneum tissue.

 

EVOLUTION_SEM_PRODOTTI

Source: Politenico di Torino, Torino, Italy.

Evolution membranes are ready to use and are the appropriate choice to stabilise the graft and avoid its contamination. 

Dentist

Why choosing Evolution?

Graft protection against bacteria and food contamination is necessary to allow hard and soft tissue healing. Thanks to their high consistency, resistance to degradation⁴ and stretchability, Evolution collagen membranes are valid solutions to maintain the bone graft stable and isolated thus reducing the risk of complications⁵⁻¹⁰,¹¹⁻¹².The structure made of dense collagen fibres³ and the appropriate gradual degradation rate prevents the infection from bacteria, thus allowing to leave the membrane exposed⁶ when treating post-extractive sockets in the molar and premolar regions.

In addition, Evolution collagen membranes allow second-intention soft tissue healing⁶ allowing adequate new bone formation⁵⁻¹⁰. More than 25 years of clinical and scientific evidence prove that Evolution collagen membranes can be used in post-extraction sockets to protect the graft⁵⁻⁶, in lateral access sinus lift to protect both the antrostomy and the sinus membrane⁷, to stabile the graft around peri-implant lesions⁸, periodontal⁹ defects, and vertical defects¹⁰.

handle-evolution

How to handle Evolution

The collagen membrane can be shaped with sterile scissors until the desired size is reached; unless the grafting site is already bleeding, the membrane should be hydrated with physiological solution. Once it acquires the desired plasticity, it must be adapted to the grafting site. In case of accidental exposure, the dense collagenic matrix of Evolution protects the graft from infection; the membrane itself will also not be infected, allowing second-intention healing⁵.

References
  1. Nannmark U et al. Clin Implant Dent Relat Res, 2008 Dec;10(4):264-70
  2. Toledano M et al. Polymers (Basel), 2020 Jun 4;12(6):1290
  3. Osorio R et al. Polymers (Basel), 2022 Aug 11;14(16):3274
  4. Vallecillo-Rivas M et al. Polymers (Basel), 2021 Sep 5;13(17):3007
  5. Barone A et al. Clin Oral Implants Res, 2015 Jul;26(7):806-13
  6. Barone A et al. J Periodontol, 2014 Jan;85(1):14-23
  7. Scarano A et al. Clin Implant Dent Relat Res, 2011 Mar;13(1):13-8
  8. Barone A et al. Clin Implant Dent Relat Res, 2016 Dec;18(6):1103-1112
  9. Esposito M et al. Eur J Oral Implantol, 2015 Autumn;8(3):233-44
  10. Felice P et al. Int J Periodontics Restorative Dent, 2013 Mar-Apr;33(2):159-66
  11. Iida T et al. Clin Oral Implants Res, 2017 Dec;28(12):1567-1576
  12. Hirota A et al. Int J Implant Dent, 2019 Aug 19;5(1):31
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Technical specifications

Description: 

  • 100% Heterologous pericardium and peritoneum tissue
  • Dried membrane with one smooth side and one micro-rough side
     
Porcine origin
Codes Size Thickness Re-entry time
EM02HS 20x20 mm 0.36-0.45 mm about 4 months
EM03HS 30x30 mm 0.36-0.45 mm about 4 months
EM03XS 30x30 mm 0.15–0.25 mm about 2 months
Equine origin
Codes Size Thickness Resorption time
EV02LLE 20x20 mm 0.15–0.25 mm about 3 months
EV03LLE 30x30 mm 0.15–0.25 mm about 3 months
EV02HHE 20x20 mm 0.36-0.45 mm about 4 months
EV03HHE 30x30 mm 0.36-0.45 mm about 4 months
EV04LLE 40x40 mm 0.26-0.35 mm about 4 months
EV06LLE 80x60 mm 0.26-0.35 mm about 3 months

Clinical cases

Evolution is used to stabilise the biomaterial

Treatment of a post-extractive socket

Prof. Antonio Barone

mp3® | Evolution

Alveolar regeneration

Evolution and mp3 are used to treat a periodontal defect

The Modified Papilla Preservation Technique

Dr. Gerd Körner

mp3® | Evolution

Periodontal regeneration

Bilateralmaxillarysinus_cover.jpg

Bilateral maxillary sinus elevation with horizontal bone regeneration

Prof. Tiziano Testori

GTO® | Evolution

Lateral access sinus lift

Ridge Augmentation cover

Ridge augmentation in the upper jaw

Prof. Antonio Barone

mp3® | Evolution

Alveolar regeneration

Videos

OsteoBiol - mp3 video 2
Lateral access sinus lift
OsteoBiol - mp3® (Maxillary sinus lift)

Next Courses

Testori LCI OsteoBiol course 2025 - Front page

Course on Sinus augmentation

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Como, Italy

Prof. Tiziano Testori, Prof. Marco Esposito & Dr. Matteo Invernizzi

Selected bibliography

Copyrighted

Flap versus flapless procedure for ridge preservation in alveolar extraction sockets: a histological evaluation in a randomized clinical trial

Clin Oral Implants Res, 2015 Jul;26(7):806-13

Barone A, Borgia V, Covani U, Ricci M, Piattelli A, Iezzi G
Copyrighted

Extraction socket healing in humans after ridge preservation techniques: comparison between flapless and flapped procedures in a randomized clinical trial

J Periodontol, 2014 Jan;85(1):14-23

Barone A, Toti P, Piattelli A, Iezzi G, Derchi G, Covani U
Open Access

Tomographic evaluation of the influence of the placement of a collagen membrane subjacent to the sinus mucosa during maxillary sinus floor augmentation: a randomized clinical trial

Int J Implant Dent, 2019 Aug 19;5(1):31

Hirota A, Lang NP, Ferri M, Fortich Mesa N, Apaza Alccayhuaman KA, Botticelli D
Copyrighted

The effectiveness of a resorbable bone substitute with a resorbable membrane in the treatment of periodontal infrabony defect - A multicenter randomised controlled trial

Eur J Oral Implantol, 2015;8(3):233-244

Esposito M, Grusovin MG, Lambert F, Matos S, Pietruska M, Rossi R, Salhi L, Buti J
Open Access

The collagen origin influences the degradation kinetics of guided bone regeneration membranes

Polymers (Basel), 2021 Sep 5;13(17):3007

Vallecillo-Rivas M, Toledano-Osorio M, Vallecillo C, Toledano M, Osorio R
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