• GTO
  • GTO
  • GTO
  • GTO
  • GTO
  • GTO
  • GTO
Case Reports
  • Tissue origin :
    Heterologous cortico-cancellous bone mix
  • Tissue collagen :
  • Physical form :
    Pre-hydrated granules and TSV Gel
  • Composition :
    80% granulated mix, 20% TSV Gel
  • Granulometry :
    600-1000 µm
  • Re-entry time :
    About 5 months
  • Packaging :
    Syringe: 0.5 cc
    Wide tip syringe: 2.0 cc
  • Product codes :
    MU0005S | 1 Syringe | 0.5 cc | Porcine
    MU0005E | 1 Syringe | 0.5 cc | Equine
    MU0020S | 1 Wide tip syringe | 2.0 cc | Porcine
    MU0020E | 1 Wide tip syringe | 2.0 cc | Equine
  • GMDN code : 46425
Heterologous bone grafting material made of a mix of collagenated cortico-cancellous granules of size ranging from 600 to1000 µm, properly blended with TSV Gel, which is a mixture of heterologous type I and III collagen gel with polyunsaturated fatty acids and a biocompatible synthetic copolymer diluted in aqueous solution. GTO® is gradually resorbed and it is extremely osteoconductive. Moreover, the preserved collagen matrix characterizing the granules facilitates blood clotting and the subsequent invasion of repairing and regenerative cells. These unique properties guarantee an excellent rate of new bone formation, delivering adequate graft volume preservation, a healthy new bony tissue and, ultimately, a successful implant rehabilitation. The presence of the same kind of granules of its progenitor, mp3®, which are very similar to human mineral bone, assures a similar biological response of the host tissue. GTO® can be used as alternative to autologous bone.
GTO® is available in two sizes (0.5 and 2.0 cc) as ready-to-use pre-hydrated biomaterial and can be easily grafted to the defect site. Thus, clinicians can skip the hydration step with saline or blood, saving time and decreasing the risk of accidental exposure to pathogens. The presence of TSV Gel ensures optimal stickiness of the material, which is also easily adaptable to the recipient site and extremely stable.
Clinical information
GTO® has been conceived as a universal biomaterial, easily adaptable to any bone defect, in association with Evolution membranes or Lamina to protect the graft. Nonetheless, thanks to its stickiness, has proven particularly effective for horizontal augmentation procedures (e.g.: two-walls defects, when the crest is resorbed) and for socket preservation cases with compromised buccal plate. GTO® can also be successfully used to treat peri-implant lesions. In case of open defects, GTO® should be grafted in consecutive layers compacting each layer with a sterile gauze.

The above clinical information is based on the experience of expert surgeons.
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